Lesion produced by N. gonorrhea

Lesion produced by N. gonorrhea

1. In male:

1. Acute anterior urethritis with inflammation of  litter’s and Cowper ‘s glands
2. Prostitutes
3. Orchitis.
4. Seminal vesiculitis.
5. Urethral strictures.

2. In female:

1. Endocervitis
2. Bartholinitis
3. Salpinigitis.
4. Vulvo-vaginitis
5. Pelvic peritonitis
6. Urethritis
7. Endometritis.
8. Oophoritis
9. Prostates.
10. Cystitis.

3. New –born infants:Purulent conjunctivitis (Ophthalmia neonatorum)

4. Other lesions in both sexes:

1. Septicaemia.
2. Ulcerative endocarditic.
3. Arthritis- dermatitis –tenosynovitis sydroeme.
4. Spondylitis deformans.
5. Iritic.
6. Gonococcal pharyngitis(In case of oral sex)

5. Complication:

In case of male : Urethral stricture.

In case of female: Sterility infertility.

Laboratory diagnosis of gonorrhea:

Steps:

1. Specimen collection:

-          Urethral swab

-          End cervical swab ((in female)

-          Prostatic secretion after supra-public message (in male).

2. Microscopic examination:

Gram staining of gonorrhea :

-   Gram negative diplococcic within polymorph nuclear leucocytes.

3. Isolation and identification from culture:

In special media like.

-          Chocolate agar media

-          Thayer –mertin media

-          Incubate, 5-10% CO₂ at 37°C

4. Biochemical test:Oxidase positive, ferments glucose (but not maltose)

5. Serological test: To detect antibody against gonococci are not useful for diagnosis.

Following may be done-

-          ELISA.

-          DNA probe assay.

6. Nucleic acid based technique:

-          Polymerase chain reaction (PCR)